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Receptors, Polymeric Immunoglobulin  

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Tipo

  • mesh:Descriptor

Definición

  • Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)

Concepto genérico

Etiquetas alternativas

  • Poly-Ig Receptor
  • Polyimmunoglobulin Receptor
  • Polymeric Ig Receptor
  • Polymeric Immunoglobulin Receptor
  • Polymeric Immunoglobulin Receptors
  • Receptor, Polyimmunoglobulin
  • Receptor, Polymeric Ig

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URI

http://data.loterre.fr/ark:/67375/JVR-B9VSNPKW-F

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