Concept information
Término preferido
Receptors, Polymeric Immunoglobulin
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Tipo
-
mesh:Descriptor
Definición
- Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
Concepto genérico
Etiquetas alternativas
- Poly-Ig Receptor
- Polyimmunoglobulin Receptor
- Polymeric Ig Receptor
- Polymeric Immunoglobulin Receptor
- Polymeric Immunoglobulin Receptors
- Receptor, Polyimmunoglobulin
- Receptor, Polymeric Ig
En otras lenguas
URI
http://data.loterre.fr/ark:/67375/JVR-B9VSNPKW-F
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