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ETS Motif  

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Tipo

  • mesh:Descriptor

Definición

  • A helix-turn-helix motif characterized by three alpha-helices and four-stranded beta-sheets arranged in the order alpha1-beta1-beta2-alpha2-alpha3-beta3-beta4. The third alpha-helix contacts the major groove of DNA. The ETS motif and the flanking amino acid sequences of Ets proteins influence the binding affinity, and the alteration of a single amino acid in the Ets domain can change its DNA binding specificity.

Concepto genérico

Etiquetas alternativas

  • ETS Domain
  • Helix-Turn-Helix, ETS-Type Domain Containing

En otras lenguas

  • francés

  • Domaine de type ETS contenant un motif hélice-tour-hélice
  • Domaine ETS

URI

http://data.loterre.fr/ark:/67375/JVR-BBCM324K-0

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