: MeSH: Retinoblastoma Protein

Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Retinoblastoma Protein

Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Retinoblastoma Protein

Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Retinoblastoma Protein

Amino Acids, Peptides, and Proteins > Proteins > Phosphoproteins > Retinoblastoma Protein

Retinoblastoma Protein

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Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.

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