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Lambert-Eaton Myasthenic Syndrome  

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Tipo

  • mesh:Descriptor

Definición

  • An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)

Concepto genérico

Etiquetas alternativas

  • Eaton-Lambert Myasthenic Syndrome
  • Eaton-Lambert Syndrome
  • Lambert-Eaton Syndrome
  • Myasthenic Syndrome, Lambert-Eaton
  • Myasthenic-Myopathic Syndrome of Eaton-Lambert
  • Myasthenic-Myopathic Syndrome of Lambert-Eaton
  • Myopathic-Myasthenic Syndrome of Eaton-Lambert
  • Myopathic-Myasthenic Syndrome of Lambert-Eaton

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-C0549M2Q-1

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