Concept information
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Oxidoreductases
Alcohol Oxidoreductases
Hydroxysteroid Dehydrogenases
17-Hydroxysteroid Dehydrogenases
Término preferido
Peroxisomal Multifunctional Protein-2
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Tipo
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mesh:Descriptor
Definición
- A dimeric protein found in liver peroxisomes that plays an important role in FATTY ACID metabolism and steroid metabolism. The dimer is formed by cleavage of a single protein precursor and contains an enoyl-CoA hydratase-2 domain and a second domain that displays (S)-3-hydroxyacyl-CoA dehydrogenase and 17-beta-estradiol dehydrogenase activities. The enzyme is stereospecific with regards to arrangement of the substrate double bonds and position of the 3-hydroxy group of the reaction intermediate. It is complemented by PEROXISOMAL BIFUNCTIONAL ENZYME, which has the opposite reaction stereospecificity.
Concepto genérico
Etiquetas alternativas
- 17-beta-Hydroxysteroid Dehydrogenase 4
- 3-alpha,7-alpha,12-alpha-Trihydroxy-5-beta-Cholest-24-enoyl-CoA Hydratase
- Peroxisomal Multifunctional Enzyme Type 2
En otras lenguas
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francés
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17-beta-Hydroxysteroid dehydrogenase 4
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Enzyme multifonctionnelle péroxysomale de type 2
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Enzyme multifonctionnelle péroxysomiale de type 2
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Protéine-2 multifonctionnelle péroxysomale
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Protéine-2 multifonctionnelle péroxysomiale
URI
http://data.loterre.fr/ark:/67375/JVR-C6LJ8KQB-7
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