Concept information
Término preferido
Complement C1
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Tipo
-
mesh:Descriptor
Definición
- The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- C1 Complement
- Complement 1
- Complement Component 1
En otras lenguas
-
francés
-
Composant C1 du complément
-
Facteur C1 du complément
-
Fraction C1 du complément
URI
http://data.loterre.fr/ark:/67375/JVR-C7BPKGCZ-K
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