Concept information
Término preferido
B7-1 Antigen
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Tipo
-
mesh:Descriptor
Definición
- A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Concepto genérico
Etiquetas alternativas
- Antigen, B7-1
- Antigens, CD80
- B7-1 Costimulatory Molecule
- B7-1 Ligand
- B-Cell Activation Antigen
- CD80 Antigen
- CD80 Antigens
En otras lenguas
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francés
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Antigène B7-1
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Antigène CD80 d'activation des lymphocytes B
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CD80
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Ligand B7-1
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Molécule co-stimulante B7-1
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Molécule costimulante B7-1
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Molécule de co-stimulation B7-1
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Molécule de costimulation B7-1
URI
http://data.loterre.fr/ark:/67375/JVR-CBT0PFHP-Q
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