Concept information
Término preferido
Ivermectin
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Tipo
-
mesh:Descriptor
Definición
- A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form. Oral preparation of ivermectin.
Concepto genérico
Etiquetas alternativas
- 70288-86-7
En otras lenguas
-
francés
-
70288-86-7
-
Ivermectin
URI
http://data.loterre.fr/ark:/67375/JVR-CCR28XBL-Q
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