Concept information
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Peptides
Intracellular Signaling Peptides and Proteins
Protein Tyrosine Phosphatases
Protein Tyrosine Phosphatases, Non-Receptor
Término preferido
Protein Tyrosine Phosphatase, Non-Receptor Type 22
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Tipo
-
mesh:Descriptor
Definición
- A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES. An alternatively spliced variant of tyrosine protein phosphatase, non-receptor type 22. An alternatively spliced variant of tyrosine protein phosphatase, non-receptor type 22.
Concepto genérico
Etiquetas alternativas
- Lymphoid Phosphatase
- Protein-Tyrosine Phosphatase Lyp
- PTPase Lyp
- PTPN-22 Protein
- Tyrosine Protein Phosphatase, Non-Receptor Type 22
En otras lenguas
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francés
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Lymphoid Phosphatase
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Phosphatase LYP
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Protéine tyrosine phosphatase Lyp
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Protéine tyrosine phosphatase non-réceptrice de type 22
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Protéine-tyrosine phosphatase non-réceptrice de type 22
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PTPase Lyp
URI
http://data.loterre.fr/ark:/67375/JVR-CWBTP8XF-L
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