Concept information
Término preferido
Simvastatin
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Tipo
-
mesh:Descriptor
Definición
- A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- 79902-63-9 (Simvastatin)
- AGG2FN16EV
En otras lenguas
-
francés
-
79902-63-9 (Simvastatin)
-
AGG2FN16EV
URI
http://data.loterre.fr/ark:/67375/JVR-D9FD2HPW-B
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