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Concept information

Término preferido

Sulindac  

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Tipo

  • mesh:Descriptor

Definición

  • A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

Concepto genérico

Etiquetas alternativas

  • 184SNS8VUH
  • 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-
  • 38194-50-2 (Sulindac)

En otras lenguas

  • francés

  • 184SNS8VUH
  • 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-
  • 38194-50-2 (Sulindac)

URI

http://data.loterre.fr/ark:/67375/JVR-DHSWQ5B2-X

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