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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > Discoidin Domain
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > Discoidin Domain

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Discoidin Domain  

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Tipo

  • mesh:Descriptor

Definición

  • A protein domain originally identified in DISCOIDINS. It occurs in a variety of unrelated proteins in multicellular organisms, where it recognizes different ligands with distinct biological functions. Structurally, it consists of two antiparallel beta sheets that form a "jellyroll" configuration stabilized by two intramolecular disulfide bonds. Sequence differences within this module determine ligand specificity; in DISCOIDIN DOMAIN RECEPTORS, it binds to FIBRILLAR COLLAGENS and NON-FIBRILLAR COLLAGENS.

Concepto genérico

Etiquetas alternativas

  • Discoidin Domains

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-DKF52SD9-T

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RDF/XML TURTLE JSON-LD Creado 8/7/16, última modificación 9/5/16