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... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Neurotransmitter Agents > GABA Agents > GABA Modulators
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Neurotransmitter Agents > GABA Agents > GABA Modulators

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GABA Modulators  

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Tipo

  • mesh:Descriptor

Definición

  • Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.

Concepto genérico

Conceptos relacionados

Etiquetas alternativas

  • GABAergic Modulators
  • gamma-Aminobutyric Acid Modulators

En otras lenguas

  • Modulateurs GABA

    francés

  • Modulateurs de l'acide amino-4 butyrique
  • Modulateurs GABAergiques

URI

http://data.loterre.fr/ark:/67375/JVR-DW8H3MNZ-P

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RDF/XML TURTLE JSON-LD Creado 3/6/94, última modificación 30/6/05