Concept information
Término preferido
25-Hydroxyvitamin D3 1-alpha-Hydroxylase
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Tipo
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mesh:Descriptor
Definición
- A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol).
Concepto genérico
Etiquetas alternativas
- 25-Hydroxycholecalciferol 1-Hydroxylase
- 25-Hydroxycholecalciferol-1-Hydroxylase
- 25-Hydroxyergocalciferol 1-alpha-Hydroxylase
- 25-Hydroxyvitamin D 1-alpha-Hydroxylase
- 25-Hydroxyvitamin D2 1-hydroxylase
- 25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase
- Calcidiol 1-Monooxygenase
- Calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)
- CYP27B1
- Cytochrome P-450 CYP27B1
En otras lenguas
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francés
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25-Hydroxycholécalciférol 1-hydroxylase
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Calcidiol 1-Monooxygénase
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Calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)
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CYP 27B1
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CYP27B1
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Cytochrome P-450 CYP27B1
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Cytochrome P450 27B1
URI
http://data.loterre.fr/ark:/67375/JVR-F1J1QCL5-M
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