Concept information
Término preferido
KRIT1 Protein
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Tipo
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mesh:Descriptor
Definición
- A microtubule-associated protein consisting of four ANKYRIN REPEATS and a C-terminal FERM DOMAIN. It links the CYTOSKELETON to CELL JUNCTIONS via integrin cytoplasmic domain-associated protein-1 and plays an important role in regulating cell proliferation and integrity of endothelial cell junctions. It is also involved in REACTIVE OXYGEN SPECIES metabolism. Mutations in the KRIT1 gene are associated with type I CEREBRAL CAVERNOUS MALFORMATIONS.
Concepto genérico
Etiquetas alternativas
- Cerebral Cavernous Malformations 1 Protein
- Krev Interaction Trapped Protein 1
En otras lenguas
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francés
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Protéine associée avec les malformations caverneuses cérébrales de type 1
URI
http://data.loterre.fr/ark:/67375/JVR-FHZ0LQ0S-4
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