Concept information
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Immunoglobulins
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Immunoglobulin Variable Region
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Immunoglobulins
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Immunoglobulin Variable Region
Término preferido
Immunoglobulin Joining Region
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Tipo
-
mesh:Descriptor
Definición
- A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.
Concepto genérico
Etiquetas alternativas
- Joining Region, Ig
En otras lenguas
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francés
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Région charnière d'immunoglobuline
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Région charnière des immunoglobulines
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Région jonction d'immunoglobuline
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Séquence jonction d'immunoglobuline
URI
http://data.loterre.fr/ark:/67375/JVR-FWZW3LMT-X
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