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Concept information

Término preferido

Immunoglobulin Joining Region  

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Tipo

  • mesh:Descriptor

Definición

  • A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.

Etiquetas alternativas

  • Joining Region, Ig

En otras lenguas

  • francés

  • Région charnière d'immunoglobuline
  • Région charnière des immunoglobulines
  • Région jonction d'immunoglobuline
  • Séquence jonction d'immunoglobuline

URI

http://data.loterre.fr/ark:/67375/JVR-FWZW3LMT-X

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RDF/XML TURTLE JSON-LD Creado 11/5/87, última modificación 25/6/10