Concept information
Término preferido
Apoptosomes
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Tipo
-
mesh:Descriptor
Definición
- Multimeric protein complexes formed in the CYTOSOL that play a role in the activation of APOPTOSIS. They can occur when MITOCHONDRIA become damaged due to cell stress and release CYTOCHROME C. Cytosolic cytochrome C associates with APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 to form the apoptosomal protein complex. The apoptosome signals apoptosis by binding to and activating specific INITIATOR CASPASES such as CASPASE 9.
Concepto genérico
Etiquetas alternativas
- Apoptosomal Protein Complex
- Apoptosome
En otras lenguas
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francés
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Apoptosome
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Complexe apoptosome
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Complexe multiprotéique de l'apoptose
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Complexe protéique de l'apoptose
URI
http://data.loterre.fr/ark:/67375/JVR-G1105Z8N-G
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