: MeSH: Peripheral Tolerance

Immune System Phenomena > Immunomodulation > Immune Tolerance > Self Tolerance > Peripheral Tolerance

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Peripheral Tolerance

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The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished through a variety of means including CLONAL ANERGY and CLONAL DELETION.

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