Concept information
Término preferido
Shelterin Complex
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Tipo
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mesh:Descriptor
Definición
- A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2).
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- POT1-TPP1 Shelterin Complex
- Telomere POT1-TPP1 Complex
- Telosome
En otras lenguas
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francés
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Complexe télomérique POT1-TPP1
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Télosome
URI
http://data.loterre.fr/ark:/67375/JVR-GJKN3KTK-5
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