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Shelterin Complex  

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Tipo

  • mesh:Descriptor

Definición

  • A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2).

Etiquetas alternativas

  • POT1-TPP1 Shelterin Complex
  • Telomere POT1-TPP1 Complex
  • Telosome

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-GJKN3KTK-5

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RDF/XML TURTLE JSON-LD Creado 9/7/21, última modificación 30/6/21