Concept information
Término preferido
Niemann-Pick C1 Protein
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Tipo
-
mesh:Descriptor
Definición
- A transmembrane intracellular lipid transporter that helps trafficking lipids, particularly cholesterol, from late endosome/lysosome to the ER and plasma membrane. It may also play a role in other cellular cholesterol homeostasis and is an endosomal entry receptor for filoviruses including EBOLAVIRUS. Mutations in the NPC1 are associated with type C NIEMANN-PICK DISEASE.
Concepto genérico
Etiquetas alternativas
- NPC1 Protein
En otras lenguas
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francés
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Protéine de Niemann-Pick C1
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Protéine Niemann-Pick C1
URI
http://data.loterre.fr/ark:/67375/JVR-GNQ4JHM7-H
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