Concept information
Immune System Diseases
Autoimmune Diseases
Autoimmune Diseases of the Nervous System
Demyelinating Autoimmune Diseases, CNS
Nervous System Diseases
Autoimmune Diseases of the Nervous System
Demyelinating Autoimmune Diseases, CNS
...
Central Nervous System Diseases
Brain Diseases
Leukoencephalopathies
Demyelinating Autoimmune Diseases, CNS
Immune System Diseases
Autoimmune Diseases
Autoimmune Diseases of the Nervous System
Nervous System Autoimmune Disease, Experimental
Nervous System Diseases
Autoimmune Diseases of the Nervous System
Nervous System Autoimmune Disease, Experimental
Término preferido
Encephalomyelitis, Autoimmune, Experimental
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Tipo
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mesh:Descriptor
Definición
- An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
Concepto genérico
Etiquetas alternativas
- Allergic Encephalomyelitis
- Allergic Encephalomyelitis, Experimental
- Autoimmune Encephalomyelitis, Experimental
- Autoimmune Experimental Encephalomyelitis
- Encephalomyelitis, Allergic
- Encephalomyelitis, Experimental Autoimmune
- Experimental Allergic Encephalomyelitis
- Experimental Autoimmune Encephalomyelitis
En otras lenguas
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francés
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EAE (Encéphalomyélite Auto-immune Expérimentale)
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Encéphalomyélite allergique
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Encéphalomyélite allergique expérimentale
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Encéphalomyélite autoimmune expérimentale
URI
http://data.loterre.fr/ark:/67375/JVR-H2DZ68Z1-B
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