Skip to main

Medical Subject Headings (thesaurus)

Search from vocabulary

mapear
anotar
descargar

Concept information

... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Pancreatic Hormones > Insulins > Proinsulin
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Pancreatic Hormones > Insulins > Proinsulin
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Proinsulin

Término preferido

Proinsulin  

Notice: Undefined index: in /var/www/html/model/Concept.php on line 545

Tipo

  • mesh:Descriptor

Definición

  • A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC BETA CELLS, is comprised sequentially of the N-terminal B-chain, the proteolytically removable connecting C-peptide, and the C-terminal A-chain. It also contains three disulfide bonds, two between A-chain and B-chain. After cleavage at two locations, insulin and C-peptide are the secreted products. Intact proinsulin with low bioactivity also is secreted in small amounts.

Concepto genérico

Conceptos específicos

Etiquetas alternativas

  • 9035-68-1

En otras lenguas

  • Proinsuline

    francés

  • 9035-68-1
  • Pro-insuline
  • Proinsulin

URI

http://data.loterre.fr/ark:/67375/JVR-H34TJ9MG-2

Descargue este concepto:

RDF/XML TURTLE JSON-LD Creado 1/1/99, última modificación 24/6/11