: MeSH: Muscle Relaxants, Central

Chemical Actions and Uses > Pharmacologic Actions > Therapeutic Uses > Central Nervous System Agents > Muscle Relaxants, Central

... > Pharmacologic Actions > Physiological Effects of Drugs > Peripheral Nervous System Agents > Neuromuscular Agents > Muscle Relaxants, Central

Muscle Relaxants, Central

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A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)

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