Skip to main

Medical Subject Headings (thesaurus)

Search from vocabulary

Concept information

Término preferido

Discs Large Homolog 1 Protein  

Notice: Undefined index: in /var/www/html/model/Concept.php on line 545

Tipo

  • mesh:Descriptor

Definición

  • A signaling adaptor protein that contains three PDZ DOMAINS; an SH3 DOMAIN; and a GUANYLATE KINASE-like C-terminal region. It has an essential role in animal development and recruits ion channels, receptors, and signaling molecules to discrete plasma membrane regions of polarized cells in the HEART ATRIA MYOCARDIUM. It functions in the assembly of ADHERENS JUNCTIONS and regulation of CELL PROLIFERATION; synaptogenesis, LYMPHOCYTE ACTIVATION; and controls expression of KV4 POTASSIUM CHANNELS to regulate excitability of CARDIAC MYOCYTES.

Etiquetas alternativas

  • Synapse-Associated Protein 97

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-HSM2M31L-2

Descargue este concepto:

RDF/XML TURTLE JSON-LD Creado 11/7/17, última modificación 27/2/17