: MeSH: Crush Syndrome

Wounds and Injuries > Shock, Traumatic > Crush Syndrome

Pathological Conditions, Signs and Symptoms > Pathologic Processes > Shock > Shock, Traumatic > Crush Syndrome

Wounds and Injuries > Crush Injuries > Crush Syndrome

Crush Syndrome

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Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.

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