Concept information
Término preferido
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Tipo
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mesh:Descriptor
Definición
- A dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. It has highest activity towards single-stranded RNA containing 3-methyluracil, followed by SINGLE-STRANDED DNA containing 3-methylthymine and specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA (mRNA) in higher EUKARYOTES. It contributes to the regulation of the global metabolic rate, energy HOMEOSTASIS, as well as body fat accumulation by regulating the differentiation of ADIPOCYTES into BROWN FAT CELLS or WHITE FAT CELLS.
Concepto genérico
Etiquetas alternativas
- AlkB Homolog 9 Protein
- Alpha-Ketoglutarate-Dependent Dioxygenase
- Fat Mass and Obesity Associated (FTO) Protein
- Fat Mass and Obesity Associated Protein
En otras lenguas
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francés
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Dioxygénase dépendante de l'alpha-cétoglutarate
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Dioxygénase dépendante de l'oxoglutarate
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Dioxygénase FTO dépendante de l'alpha-cétoglutarate
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Dioxygénase FTO dépendante de l'oxoglutarate
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Fat mass and obesity associated (FTO) protein
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Protéine associée à la masse grasse et à l'obésité
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Protéine-9 homologue de AlkB
URI
http://data.loterre.fr/ark:/67375/JVR-HWTRVP58-P
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