Skip to main

Medical Subject Headings (thesaurus)

Search from vocabulary

Concept information

Término preferido

Colorectal Neoplasms, Hereditary Nonpolyposis  

Notice: Undefined index: in /var/www/html/model/Concept.php on line 545

Tipo

  • mesh:Descriptor

Definición

  • A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer. HNPCC with no history of associated cancers.

Conceptos específicos

Etiquetas alternativas

  • Familial Nonpolyposis Colon Cancer
  • Hereditary Nonpolyposis Colorectal Neoplasms

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-J72D4TKD-M

Descargue este concepto:

RDF/XML TURTLE JSON-LD Creado 24/6/86, última modificación 5/3/21