Concept information
Término preferido
alpha-Mannosidase
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Tipo
-
mesh:Descriptor
Definición
- An enzyme that catalyzes the HYDROLYSIS of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. The enzyme plays a role in the processing of newly formed N-glycans and in degradation of mature GLYCOPROTEINS. There are multiple isoforms of alpha-mannosidase, each having its own specific cellular location and pH optimum. Defects in the lysosomal form of the enzyme results in a buildup of mannoside intermediate metabolites and the disease ALPHA-MANNOSIDOSIS.
Concepto genérico
Etiquetas alternativas
- alpha-D-Mannosidase
- alpha-D-Mannoside Mannohydrolase
- Neutral alpha-Mannosidase
En otras lenguas
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francés
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alpha-D-Mannosidase
URI
http://data.loterre.fr/ark:/67375/JVR-JDTMB7QW-R
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