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Nervous System Diseases > Neurodegenerative Diseases > Prion Diseases
Nervous System Diseases > Central Nervous System Diseases > Central Nervous System Infections > Prion Diseases
Infections > Central Nervous System Infections > Prion Diseases

Término preferido

Prion Diseases  

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Tipo

  • mesh:Descriptor

Definición

  • A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)

Concepto genérico

Conceptos específicos

Conceptos relacionados

Etiquetas alternativas

  • Dementias, Transmissible
  • Encephalopathies, Spongiform, Transmissible
  • Prion Disease
  • Prion Protein Diseases
  • Prion-Associated Disorders
  • Prion-Induced Disorder
  • Prion-Induced Disorders
  • Spongiform Encephalopathies, Transmissible
  • Transmissible Dementias
  • Transmissible Spongiform Encephalopathies

En otras lenguas

  • Maladies à prions

    francés

  • Démences transmissibles
  • Encéphalopathies spongiformes transmissibles
  • EST (Encéphalopathie Spongiforme Transmissible)
  • Maladies à prion

URI

http://data.loterre.fr/ark:/67375/JVR-JN2F94PZ-Q

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