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Mitochondrial Permeability Transition Pore  

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Tipo

  • mesh:Descriptor

Definición

  • A multiprotein inner mitochondrial complex which opens only under certain pathological conditions (e.g., OXIDATIVE STRESS) uncoupling the membrane leading to APOPTOSIS and MITOCHONDRIAL TRANSMEMBRANE PERMEABILITY-DRIVEN NECROSIS particularly in CARDIOMYOCYTES during MYOCARDIAL REPERFUSION INJURY.

Etiquetas alternativas

  • Mitochondrial Megachannel
  • Mitochondrial Permeability Transition Pore (mPTP)
  • mPTP Protein

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-JNBD52V9-5

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