Concept information
Término preferido
Mast Cell Activation Disorders
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Tipo
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mesh:Descriptor
Definición
- A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- Mast Cell Activation Disease
- Mast Cell Disease
- Mast-Cell Disease
En otras lenguas
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francés
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Maladie d'activation mastocytaire
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Maladie des mastocytes
URI
http://data.loterre.fr/ark:/67375/JVR-KHBHJ973-G
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