Concept information
Término preferido
Troponin I
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Tipo
-
mesh:Descriptor
Definición
- A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Concepto genérico
Etiquetas alternativas
- Troponin-I
En otras lenguas
-
francés
URI
http://data.loterre.fr/ark:/67375/JVR-KKSPB8VG-Z
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