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Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > F-Box-WD Repeat-Containing Protein 7
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > F-Box Proteins > F-Box-WD Repeat-Containing Protein 7
... > Enzymes and Coenzymes > Enzymes > Ligases > Ubiquitin-Protein Ligase Complexes > Ubiquitin-Protein Ligases > SKP Cullin F-Box Protein Ligases > F-Box-WD Repeat-Containing Protein 7

Término preferido

F-Box-WD Repeat-Containing Protein 7  

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Tipo

  • mesh:Descriptor

Definición

  • A component of SCF(FBW7) UBIQUITIN LIGASE that contains an F-box motif and multiple WD REPEATS. It recognizes and binds phosphorylated signals in several proteins involved in CELL PROLIFERATION and targets them to the SCF complex for UBIQUITINATION. Targets include CYCLIN E; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MYC; and JNK MITOGEN-ACTIVATED PROTEIN KINASES.

Concepto genérico

Etiquetas alternativas

  • F-Box and WD-40 Domain-Containing Protein 7
  • FBXW7 Protein

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-KQ1PJH0D-S

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RDF/XML TURTLE JSON-LD Creado 11/7/17, última modificación 27/2/17