Concept information
Término preferido
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
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Tipo
-
mesh:Descriptor
Definición
- Phosphoinositide phosphatases that catalyze the dephosphorylation (hydrolysis) of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) to produce PtdIns(3,4)P(2), which negatively regulates the PI3K ( 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES) pathways. They contain an SH2 DOMAIN and STERILE ALPHA MOTIF and have important functions in regulating the immune response and other cellular processes in vertebrates.
Concepto genérico
Etiquetas alternativas
- SHIP Phosphatases
- Src Homology 2 Domain-Containing Inositol Phosphatases
En otras lenguas
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francés
-
Inositol phosphtases contenant un domaine homologue de SRC de type 2
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Inositol phosphtases contenant un domaine-2 homologue de SRC
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Phosphatases SHIP
URI
http://data.loterre.fr/ark:/67375/JVR-KV7L8J51-C
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