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Diphtheria Toxin  

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Tipo

  • mesh:Descriptor

Definición

  • An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains MONO(ADP-RIBOSE) TRANSFERASES which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.

Etiquetas alternativas

  • Corynebacterium Diphtheriae Toxin
  • Toxin, Corynebacterium Diphtheriae

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-KWJMKS1Z-3

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