Concept information
Término preferido
Hypoxanthine Phosphoribosyltransferase
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Tipo
-
mesh:Descriptor
Definición
- An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or MERCAPTOPURINE to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the LESCH-NYHAN SYNDROME, while partial deficiency results in overproduction of uric acid. EC 2.4.2.8.
Concepto genérico
Etiquetas alternativas
- 9016-12-0 (CAS RN)
- Guanine Phosphoribosyltransferase
- HGPRT
- HPRT
- HPRTase
- Hypoxanthine-Guanine Phosphoribosyltransferase
- IMP Pyrophosphorylase
- IMP:pyrophosphate phospho-D-ribosyltransferase
En otras lenguas
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francés
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9016-12-0 (CAS RN)
-
Guanine phosphoribosyltransférase
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IMP pyrophosphorylase
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IMP:pyrophosphate phospho-D-ribosyltransferase
URI
http://data.loterre.fr/ark:/67375/JVR-KX7K4FRV-Z
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