Concept information
Biological Factors
Intercellular Signaling Peptides and Proteins
Angiogenic Proteins
Vascular Endothelial Growth Factors
Término preferido
Placenta Growth Factor
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Tipo
-
mesh:Descriptor
Definición
- An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
Concepto genérico
Etiquetas alternativas
- 144589-93-5
En otras lenguas
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francés
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144589-93-5
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Facteur de croissance du placenta
URI
http://data.loterre.fr/ark:/67375/JVR-L1615X39-X
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