: MeSH: Protein Aggregation, Pathological

Chemical Phenomena > Biochemical Phenomena > Protein Aggregation, Pathological

Pathological Conditions, Signs and Symptoms > Pathologic Processes > Protein Aggregation, Pathological

Protein Aggregation, Pathological

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A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.

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