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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Mediator Complex
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Mediator Complex
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Mediator Complex
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Mediator Complex
Macromolecular Substances > Multiprotein Complexes > Mediator Complex

Término preferido

Mediator Complex  

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Tipo

  • mesh:Descriptor

Definición

  • A large protein complex which acts as a signaling adaptor protein that allows communication between the various regulatory and functional components of GENETIC TRANSCRIPTION including DNA POLYMERASE II; GENERAL TRANSCRIPTION FACTORS; and TRANSCRIPTION FACTORS that are bound to upstream ENHANCER ELEMENTS. The mediator complex was originally studied in YEAST where at least 21 subunits were identified. Many of the yeast subunits are homologs to proteins in higher organisms that are found associated with specific nuclear receptors such as THYROID HORMONE RECEPTORS and VITAMIN D RECEPTORS.

Concepto genérico

Conceptos específicos

Etiquetas alternativas

  • Mediator Transcription Complex

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-LMFXKCX2-0

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RDF/XML TURTLE JSON-LD Creado 6/7/09, última modificación 30/3/16