: MeSH: Zinc Finger E-box Binding Homeobox 2

Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Homeodomain Proteins > Zinc Finger E-box Binding Homeobox 2

Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > Zinc Finger E-box Binding Homeobox 2

Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > Zinc Finger E-box Binding Homeobox 2

Zinc Finger E-box Binding Homeobox 2

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A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.

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