Concept information
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Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Término preferido
Receptor, trkA
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Tipo
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mesh:Descriptor
Definición
- A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis.
Concepto genérico
Etiquetas alternativas
- c-trk Protein
- gp140 c-trk
- gp140(c-TRK)
- Neurotrophic Tyrosine Kinase Receptor Type 1
- NTRK1 Receptor
- p140-trkA
- Proto-Oncogene Products c-trk
- Proto-Oncogene Protein trk
- Receptor, Neurotrophic Tyrosine Kinase Type 1
- trk Proto-Oncogene Protein
- trk1 Transforming Tryrosine Kinase
- trkA Receptor
En otras lenguas
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francés
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Protéine proto-oncogène trk
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Récepteur NTRK1
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Récepteur tyrosine kinase neurotrophique type 1
URI
http://data.loterre.fr/ark:/67375/JVR-M0793Z0H-T
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