Skip to main

Medical Subject Headings (thesaurus)

Search from vocabulary

mapear
anotar
descargar

Concept information

Metabolism > Pharmacokinetics > Biotransformation > Inactivation, Metabolic > Metabolic Detoxication, Phase I
... > Physiological Phenomena > Pharmacological and Toxicological Phenomena > Pharmacokinetics > Biotransformation > Inactivation, Metabolic > Metabolic Detoxication, Phase I

Término preferido

Metabolic Detoxication, Phase I  

Notice: Undefined index: in /var/www/html/model/Concept.php on line 545

Tipo

  • mesh:Descriptor

Definición

  • Functionalization of exogenous substances to prepare them for conjugation in PHASE II DETOXIFICATION. Phase I enzymes include CYTOCHROME P450 enzymes and some OXIDOREDUCTASES. Excess induction of phase I over phase II detoxification leads to higher levels of FREE RADICALS that can induce CANCER and other cell damage. Induction or antagonism of phase I detoxication is the basis of a number of DRUG INTERACTIONS.

Concepto genérico

Conceptos relacionados

Etiquetas alternativas

  • Metabolic Detoxication, Oxidative
  • Metabolic Detoxification, Phase I
  • Phase I Detoxification

En otras lenguas

  • Détoxication de phase I

    francés

  • Détoxication métabolique de phase I
  • Détoxication oxydative
  • Détoxication par oxydation
  • Détoxification de phase I
  • Détoxification métabolique de phase I
  • Détoxification oxydative
  • Détoxification par oxydation

URI

http://data.loterre.fr/ark:/67375/JVR-MD3PXP2B-J

Descargue este concepto:

RDF/XML TURTLE JSON-LD Creado 30/6/05, última modificación 30/6/16