Concept information
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DNA-Binding Proteins
Basic Helix-Loop-Helix Transcription Factors
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Sterol Regulatory Element Binding Proteins
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Transcription Factors
Basic Helix-Loop-Helix Transcription Factors
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Sterol Regulatory Element Binding Proteins
Término preferido
Sterol Regulatory Element Binding Protein 1
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Tipo
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mesh:Descriptor
Definición
- A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING. SREBP1-C is an isoform of sterol regulatory element binding protein 1 that is a weak activator of GENETIC TRANSCRIPTION. It is the predominant form in LIVER and ADIPOCYTES, and it mediates INSULIN induced FATTY ACIDS synthesis. SREBP1-A is an isoform of sterol regulatory element binding protein 1 that is a potent activator of GENETIC TRANSCRIPTION. It is the predominant form in SPLEEN.
Concepto genérico
Etiquetas alternativas
- SRE-1 Binding Protein
- SREBP1 Protein
- Sterol Regulatory Element-Binding Protein 1
En otras lenguas
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francés
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Facteur de transcription SREBP-1
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Facteur de transcription SREBP1
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Facteur SREBP-1
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Facteur transcriptionnel SREBP-1
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Facteur transcriptionnel SREBP1
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Protéine SREBP-1
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Protéine SREBP1
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Protéine-1 de fixation à l'élément de régulation des stérols
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Protéine-1 se fixant à l'élément de régulation des stérols
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Protéine-1 se liant à l'élément de régulation des stérols
URI
http://data.loterre.fr/ark:/67375/JVR-MQ11VK15-M
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