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Investigative Techniques > Genetic Techniques > Nucleic Acid Denaturation
Chemical Phenomena > Biochemical Phenomena > Nucleic Acid Denaturation
Genetic Phenomena > Nucleic Acid Denaturation

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Nucleic Acid Denaturation  

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Tipo

  • mesh:Descriptor

Definición

  • Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.

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http://data.loterre.fr/ark:/67375/JVR-N0M5B5TV-N

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