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Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Receptors, Steroid > Pregnane X Receptor
Amino Acids, Peptides, and Proteins > Proteins > Receptors, Cytoplasmic and Nuclear > Receptors, Steroid > Pregnane X Receptor

Término preferido

Pregnane X Receptor  

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Tipo

  • mesh:Descriptor

Definición

  • Steroid receptor that binds and is activated by variety of endogenous compounds and XENOBIOTICS. It binds the response element in promoters of genes that encode CYTOCHROME P450 3A4 and ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 proteins, and also activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs, and endogenous compounds. It is activated by the antibiotic RIFAMPICIN and various plant metabolites, such as hyperforin, guggulipid, colupulone, and ISOFLAVONES.

Concepto genérico

Etiquetas alternativas

  • NR1I2
  • Nuclear Receptor Subfamily 1, Group I, Member 2
  • Steroid and Xenobiotic Receptor
  • Steroid X Receptor
  • SXR Receptor

En otras lenguas

  • Récepteur du prégnane X

    francés

  • Membre-2 du groupe I de la sous-famille-1 de récepteurs nucléaires
  • NR1I2
  • Récepteur des stéroïdes et des xénobiotiques
  • Récepteur des stéroïdes et xénobiotiques
  • Récepteur prégnane X
  • Récepteur SXR

URI

http://data.loterre.fr/ark:/67375/JVR-N4WFTJ0T-D

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RDF/XML TURTLE JSON-LD Creado 9/7/18, última modificación 28/2/18