Concept information
Término preferido
Methylenetetrahydrofolate Dehydrogenase (NADP)
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Tipo
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mesh:Descriptor
Definición
- An NADP-dependent oxidoreductase that catalyses the conversion of 5,10-methyleneterahydrofolate to 5,10-methenyl-tetrahydrofolate. In higher eukaryotes a trifunctional enzyme exists with additional METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE and FORMATE-TETRAHYDROFOLATE LIGASE activity. The enzyme plays an important role in the synthesis of 5-methyltetrahydrofolate, the methyl donor for the VITAMIN B12-dependent remethylation of HOMOCYSTEINE to METHIONINE via METHIONINE SYNTHETASE.
Concepto genérico
Etiquetas alternativas
- 5,10-Methylenetetrahydrofolate:NADP+ oxidoreductase
- Methylenetetrahydrofolate Dehydrogenase
- Methylenetetrahydrofolate Dehydrogenase (NADP+)
En otras lenguas
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francés
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(NADP) Méthylène tétrahydrofolate déshydrogénase
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5,10-Methylenetetrahydrofolate:NADP+ oxidoreductase
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Méthylène-THF déshydrogénase
URI
http://data.loterre.fr/ark:/67375/JVR-N7D8Q4ZL-F
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