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Presenilins  

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Tipo

  • mesh:Descriptor

Definición

  • Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.

Concepto genérico

Conceptos específicos

Etiquetas alternativas

  • Presenilin

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-P3BTM0K8-H

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