Concept information
Término preferido
Filamins
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Tipo
-
mesh:Descriptor
Definición
- A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.
Concepto genérico
Etiquetas alternativas
- Filamin
En otras lenguas
-
francés
-
Filamine
URI
http://data.loterre.fr/ark:/67375/JVR-P449VH1K-N
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