Concept information
Término preferido
Cyclin-Dependent Kinase Inhibitor Proteins
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Tipo
-
mesh:Descriptor
Definición
- A group of cell cycle proteins that negatively regulate the activity of CYCLIN/CYCLIN-DEPENDENT KINASE complexes. They inhibit CELL CYCLE progression and help control CELL PROLIFERATION following GENOTOXIC STRESS as well as during CELL DIFFERENTIATION. A family of cell cycle proteins containing ANKYRIN REPEATS that are specific inhibitors of cyclin D-dependent kinases. INK4 proteins bind to CYCLIN-DEPENDENT KINASE 4 and CYCLIN-DEPENDENT KINASE 6. They dissociate cyclin-CDK complexes and regulate a CELL CYCLE checkpoint in early G1 PHASE.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- CDKI Proteins
- CKI Proteins
- Cyclin-Kinase Inhibitor Proteins
En otras lenguas
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francés
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CDKI
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CKI (Cyclin-dependent Kinase Inhibitor)
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CKI (Cyclin-Kinase Inhibitor)
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Cyclin-dependent kinase inhibitor
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Cyclin-kinase inhibitor
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Protéines CDKI
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Protéines CKI
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Protéines inhibitrices des CDK
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Protéines inhibitrices des kinases dépendantes des cyclines
URI
http://data.loterre.fr/ark:/67375/JVR-P5K3DBDP-J
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