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Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Piperidines > Piperidones > Thalidomide
... > Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Isoindoles > Phthalimides > Thalidomide
Organic Chemicals > Imides > Phthalimides > Thalidomide
... > Organic Chemicals > Carboxylic Acids > Acids, Carbocyclic > Phthalic Acids > Phthalimides > Thalidomide

Término preferido

Thalidomide  

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Tipo

  • mesh:Descriptor

Definición

  • A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.

Concepto genérico

Etiquetas alternativas

  • 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
  • 4Z8R6ORS6L
  • 50-35-1 (Thalidomide)

En otras lenguas

  • Thalidomide

    francés

  • 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
  • 4Z8R6ORS6L
  • 50-35-1 (Thalidomide)

URI

http://data.loterre.fr/ark:/67375/JVR-PC6PGQ3C-6

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